3-(Methylsulphonyl)aniline → HCID 67095787, compound
Reaction equation
I[C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][C:6](Cl)=[N:7]2.[CH3:13][O:14][C:15]1[CH:23]=[C:22]2[C:18]([CH2:19][CH2:20][CH:21]2[NH2:24])=[CH:17][CH:16]=1.[CH3:25][S:26]([C:29]1[CH:30]=[C:31]([CH:33]=[CH:34][CH:35]=1)[NH2:32])(=[O:28])=[O:27]>>[CH3:25][S:26]([C:29]1[CH:30]=[C:31]([NH:32][C:2]2[C:3]3[CH:4]=[CH:5][C:6]([NH:24][CH:21]4[C:22]5[C:18](=[CH:17][CH:16]=[C:15]([O:14][CH3:13])[CH:23]=5)[CH2:19][CH2:20]4)=[N:7][C:8]=3[CH:9]=[CH:10][CH:11]=2)[CH:33]=[CH:34][CH:35]=1)(=[O:27])=[O:28]Participants
4
Procedure
The title compound, MS: m/e=460.4 (M+H+), was prepared in accordance with the general method of example 6 from 5-iodo-2-chloroquinoline, 6-methoxyindan-1-ylamine (CAS 103028-81-5) and 3-methylsulfonylaniline.
Sources & evidence
- ORD record
- ord-6926076a85a447fbbac2aa1a186f1bdb
- Source dataset
- uspto-grants-2011_04
- Patent number
- US07923561B2
Reaction notes
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