4-Fluorobenzenesulfonyl chloride → HCID 67095804, compound

HRID 2076299Notes

Reaction equation

HRID 2076299 reaction equation
[N+:1]([C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[CH:7][C:8](Cl)=[N:9]2)([O-])=O.[F:15][C:16]1[CH:21]=[CH:20][C:19]([S:22](Cl)(=[O:24])=[O:23])=[CH:18][CH:17]=1.[NH2:26][CH:27]1[C:36]2[C:31](=[C:32]([O:39][CH3:40])[CH:33]=[CH:34][C:35]=2[O:37][CH3:38])[CH2:30][CH2:29][CH2:28]1>>[CH3:40][O:39][C:32]1[CH:33]=[CH:34][C:35]([O:37][CH3:38])=[C:36]2[C:31]=1[CH2:30][CH2:29][CH2:28][CH:27]2[NH:26][C:8]1[CH:7]=[CH:6][C:5]2[C:10](=[CH:11][CH:12]=[CH:13][C:4]=2[NH:1][S:22]([C:19]2[CH:20]=[CH:21][C:16]([F:15])=[CH:17][CH:18]=2)(=[O:24])=[O:23])[N:9]=1

Participants

4

Reactant 3

HCID 95884-Fluorobenzenesulfonyl chlorideHCID 46449HCID 46449, compoundHCID 3192512-Chloro-5-nitroquinoline

Product 1

HCID 67095804HCID 67095804, compound

Procedure

The title compound, MS: m/e=508.4 (M+H+), was prepared in accordance with the general method of example 13 from 5-nitro-2-chloroquinoline, 4-fluorobenzenesulfonyl chloride and rac-1-amino-5,8-dimethoxy-1,2,3,4-tetrahydro-naphthalene (CAS 784988-69-8).

Sources & evidence

ORD record
ord-e12c1c9d79f9417fbb74000ba9a95f18
Source dataset
uspto-grants-2011_04
Patent number
US07923561B2

Reaction notes

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