2-Chloro-5-nitroquinoline → HCID 25019576, compound

HRID 2076301Notes

Reaction equation

HRID 2076301 reaction equation
[N+:1]([C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[CH:7][C:8](Cl)=[N:9]2)([O-])=O.[F:15][C:16]1[CH:17]=[C:18]([S:23](Cl)(=[O:25])=[O:24])[CH:19]=[C:20]([F:22])[CH:21]=1.[CH3:27][O:28][C:29]1[CH:30]=[CH:31][CH:32]=[C:33]2[C:37]=1[CH:36]([NH2:38])[CH2:35][CH2:34]2>>[F:15][C:16]1[CH:17]=[C:18]([S:23]([NH:1][C:4]2[CH:13]=[CH:12][CH:11]=[C:10]3[C:5]=2[CH:6]=[CH:7][C:8]([NH:38][CH:36]2[C:37]4[C:33](=[CH:32][CH:31]=[CH:30][C:29]=4[O:28][CH3:27])[CH2:34][CH2:35]2)=[N:9]3)(=[O:25])=[O:24])[CH:19]=[C:20]([F:22])[CH:21]=1

Participants

4

Reactant 3

HCID 3192512-Chloro-5-nitroquinolineHCID 27740583,5-Difluorobenzenesulfonyl chlorideHCID 186198817-Methoxy-2,3-dihydro-1H-inden-1-amine

Product 1

HCID 25019576HCID 25019576, compound

Procedure

The title compound, MS: m/e=482.5 (M+H+), was prepared in accordance with the general method of example 13 from 5-nitro-2-chloroquinoline, 3,5-difluorobenzenesulfonyl chloride and rac-7-methoxy-indane-1-ylamine.

Sources & evidence

ORD record
ord-2e31d2d501654a2c84bf67bf45aaa233
Source dataset
uspto-grants-2011_04
Patent number
US07923561B2

Reaction notes

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