2-Chloro-5-nitroquinoline → HCID 67095794, compound

HRID 2076302Notes

Reaction equation

HRID 2076302 reaction equation
[N+:1]([C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[CH:7][C:8](Cl)=[N:9]2)([O-])=O.[F:15][C:16]1[CH:17]=[C:18]([S:23](Cl)(=[O:25])=[O:24])[CH:19]=[C:20]([F:22])[CH:21]=1.[CH3:27][O:28][C:29]1[CH:37]=[CH:36][CH:35]=[C:34]2[C:30]=1[CH2:31][CH2:32][CH:33]2[NH2:38]>>[F:15][C:16]1[CH:17]=[C:18]([S:23]([NH:1][C:4]2[CH:13]=[CH:12][CH:11]=[C:10]3[C:5]=2[CH:6]=[CH:7][C:8]([NH:38][CH:33]2[C:34]4[C:30](=[C:29]([O:28][CH3:27])[CH:37]=[CH:36][CH:35]=4)[CH2:31][CH2:32]2)=[N:9]3)(=[O:25])=[O:24])[CH:19]=[C:20]([F:22])[CH:21]=1

Participants

4

Reactant 3

HCID 3192512-Chloro-5-nitroquinolineHCID 27740583,5-Difluorobenzenesulfonyl chlorideHCID 30167414-Methoxy-2,3-dihydro-1H-inden-1-amine

Product 1

HCID 67095794HCID 67095794, compound

Procedure

The title compound, MS: m/e=482.5 (M+H+), was prepared in accordance with the general method of example 13 from 5-nitro-2-chloroquinoline, 3,5-difluorobenzenesulfonyl chloride and rac-4-methoxy-indane-1-ylamine

Sources & evidence

ORD record
ord-ecd8b30a15d146a0869fc7c1d19f8006
Source dataset
uspto-grants-2011_04
Patent number
US07923561B2

Reaction notes

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