2-Chloro-5-nitroquinoline → HCID 67095967, compound

HRID 2076312Notes

Reaction equation

HRID 2076312 reaction equation
[N+:1]([C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[CH:7][C:8](Cl)=[N:9]2)([O-])=O.[CH3:15][O:16][C:17]1[CH:18]=[CH:19][CH:20]=[C:21]2[C:25]=1[CH:24]([NH2:26])[CH2:23][CH2:22]2.[NH:27]1[C:35]2[CH:34]=[CH:33][CH:32]=[C:31]([CH:36]=O)[C:30]=2[CH:29]=[CH:28]1>>[NH:27]1[C:35]2[C:30](=[C:31]([CH2:36][NH:1][C:4]3[C:5]4[CH:6]=[CH:7][C:8]([NH:26][CH:24]5[C:25]6[C:21](=[CH:20][CH:19]=[CH:18][C:17]=6[O:16][CH3:15])[CH2:22][CH2:23]5)=[N:9][C:10]=4[CH:11]=[CH:12][CH:13]=3)[CH:32]=[CH:33][CH:34]=2)[CH:29]=[CH:28]1

Participants

4

Reactant 3

HCID 3192512-Chloro-5-nitroquinolineHCID 333703Indole-4-carboxaldehydeHCID 186198817-Methoxy-2,3-dihydro-1H-inden-1-amine

Product 1

HCID 67095967HCID 67095967, compound

Procedure

The title compound, MS: m/e=435.4 (M+H+), was prepared in accordance with the general method of example 43 from 5-nitro-2-chloroquinoline, rac-7-methoxy-indane-1-ylamine and indole-4-carbaldehyde.

Sources & evidence

ORD record
ord-5206dc65d8ed474fb82ee72eabaa2db8
Source dataset
uspto-grants-2011_04
Patent number
US07923561B2

Reaction notes

Loading…