HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-5-nitroquinoline → Rac-1-methyl-1h-indole-4-sulfonic acid [2-(7-methoxy-indan-1-ylamino)-quinolin-5-yl]-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-5-nitroquinoline | HCID 319251 | — |
| Reactant | 1-methyl-1H-indole-4-sulfonyl chloride | HCID 18525782 | — |
| Reactant | 7-Methoxy-2,3-dihydro-1H-inden-1-amine | HCID 18619881 | — |
| Product | Rac-1-methyl-1h-indole-4-sulfonic acid [2-(7-methoxy-indan-1-ylamino)-quinolin-5-yl]-amide | HCID 25019328 | — |
Reaction Steps
The title compound, MS: m/e=499.0 (M+H+), was prepared in accordance with the general method of example 45 from 5-nitro-2-chloroquinoline, rac-7-methoxy-indane-1-ylamine and 1-methyl-1H-indole-4-sulfonylchloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07923561B2 |
| Source dataset | uspto-grants-2011_04 |
| ORD ID | ord-84b80179b4484f7788a30fdee1fca68f |
| Source note | uspto-grants-2011_04 |