(R)-(-)-1-Aminoindan → HCID 25016500, compound

HRID 2076323Notes

Reaction equation

HRID 2076323 reaction equation
I[C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][C:6](Cl)=[N:7]2.[NH2:13][C@H:14]1[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[CH2:16][CH2:15]1.[Cl:23][C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][C:25]=1B(O)O>>[Cl:23][C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][C:25]=1[C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][C:6]([NH:13][C@H:14]1[C:22]3[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=3)[CH2:16][CH2:15]1)=[N:7]2

Participants

4

Reactant 3

HCID 2733933(R)-(-)-1-AminoindanHCID 27343222-Chlorophenylboronic acidHCID 457894242-Chloro-5-iodoquinoline

Product 1

HCID 25016500HCID 25016500, compound

Procedure

The title compound, MS: m/e=371.0 (M+H+), was prepared in accordance with the general method of example 63 from 5-iodo-2-chloroquinoline, (R)-1-aminoindane and 2-chlorophenyl-boronic acid.

Sources & evidence

ORD record
ord-c71ba5eb11514f64b658f947ec6a2ffb
Source dataset
uspto-grants-2011_04
Patent number
US07923561B2

Reaction notes

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