2-Aminoindane → HCID 25015976, compound

HRID 2076332Notes

Reaction equation

HRID 2076332 reaction equation
[N+:1]([C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[CH:7][C:8](Cl)=[N:9]2)([O-])=O.[NH2:15][CH:16]1[CH2:24][C:23]2[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=2)[CH2:17]1.[F:25][C:26]1[CH:27]=[C:28]([CH:31]=[C:32]([F:34])[CH:33]=1)[CH:29]=O>>[F:25][C:26]1[CH:27]=[C:28]([CH:31]=[C:32]([F:34])[CH:33]=1)[CH2:29][NH:1][C:4]1[C:5]2[CH:6]=[CH:7][C:8]([NH:15][CH:16]3[CH2:24][C:23]4[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=4)[CH2:17]3)=[N:9][C:10]=2[CH:11]=[CH:12][CH:13]=1

Participants

4

Reactant 3

HCID 763102-AminoindaneHCID 3192512-Chloro-5-nitroquinolineHCID 5881603,5-Difluorobenzaldehyde

Product 1

HCID 25015976HCID 25015976, compound

Procedure

The title compound, MS: m/e=402.4 (M+H+), was prepared in accordance with the general method of example 43 from 5-nitro-2-chloroquinoline, 2-aminoindane and 3,5-difluorobenzaldehyde.

Sources & evidence

ORD record
ord-8b1a29c5c14f4cd28252a02b937ae858
Source dataset
uspto-grants-2011_04
Patent number
US07923561B2

Reaction notes

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