Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2076455Generated: October 31, 2026

Cyclohexanecarboxylic acid → 8-Chloro-3-cyclobutylimidazo[1,5-a]pyrazine

https://huagongshe.com/reaction/2076455

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclohexanecarboxylic acidHCID 7413—
ReactantCyclobutanecarboxylic acidHCID 19494—
ReactantHCID 178501055HCID 178501055—
ReactantHCID 178501155HCID 178501155—
Product8-Chloro-3-cyclobutylimidazo[1,5-a]pyrazineHCID 42609363—

Reaction Steps

This compound was prepared using procedures analogous to that described for trans-methyl 4-(8-chloroimidazo[1,5-a]pyrazin-3-yl)cyclohexanecarboxylate and its precursor trans-methyl 4-({[(3-chloropyrazin-2-yl)methyl]amino}carbonyl)cyclohexanecarboxylate, using cyclobutanecarboxylic acid in place of 4<methoxycarbonyl)cyclohexanecarboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07923555B2
Source datasetuspto-grants-2011_04
ORD IDord-3470924747ec42bbacb3c3667aab2144
Source noteuspto-grants-2011_04