Tert-butyl 6-(bromomethyl)-2-[(tert-butoxycarbonyl)oxy]-3-(trifluoromethyl)benzoate → HCID 11504075, compound

Participants

Reaction Steps

According to a method similar to Example (40-2), Example (33-5) and Example (13-5), using allyl 4′-hydroxy-1,1′-biphenyl-4-carboxylate (190 mg, 0.75 mmol) obtained in Example (43-1) and tert-butyl 6-(bromomethyl)-2-[(tert-butoxycarbonyl)oxy]-3-(trifluoromethyl)benzoate (400 mg, 0.88 mmol) obtained in Example (28-5), the title compound was obtained as a colorless powder (293 mg, three-step total yield: 80%).

Provenance & Evidence