反应详情

According to a method similar to Example (49), from (4′-([2-(tert-butoxycarbonyl)-3-hydroxy-4-(trifluoromethyl)benzyl]oxy)-1,1′-biphenyl-4-yl)acetic acid (216 mg, 0.431 mmol) obtained in Example (7) and methylamine hydrochloride (50 mg, 0.74 mmol), the title compound was obtained as a colorless crystal (160 mg, yield: 72%).