Methyl 2-(3-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetate → HCID 67119101, compound

Participants

Reaction Steps

According to a method similar to Example (76-1), from tert-butyl 6-{[(6-chloro-3-pyridinyl)oxy]methyl}-2-hydroxy-3-(trifluoromethyl)benzoate (240 mg, 0.59 mmol) obtained in Example (84-1) and methyl [3-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acetate (224 mg, 0.77 mmol) obtained in Example (84-3), tert-butyl 2-hydroxy-6-{[(6-{4-[(methoxycarbonyl)methyl]-2-methylphenyl}-3-pyridinyl)oxy]methyl}-3-(trifluoromethyl)benzoate was obtained (157 mg, yield: 50%).

Provenance & Evidence