HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl 6-(bromomethyl)-2-[(tert-butoxycarbonyl)oxy]-3-(trifluoromethyl)benzoate → HCID 11562788, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl 6-(bromomethyl)-2-[(tert-butoxycarbonyl)oxy]-3-(trifluoromethyl)benzoate | HCID 67119234 | — |
| Reactant | HCID 86241404 | HCID 86241404 | — |
| Product | HCID 11562788 | HCID 11562788 | 46% |
Reaction Steps
According to a method similar to Example (40-2), Example (33-5) and Example (17-4), from methyl (3-ethyl-4′-hydroxy-1,1′-biphenyl-4-yl)acetate (122 mg, 0.45 mmol) synthesized in Example (85-4) and tert-butyl 6-(bromomethyl)-2-[(tert-butoxycarbonyl)oxy]-3-(trifluoromethyl)benzoate (226 mg, 0.50 mmol) obtained in Example (28-5), the title compound was obtained (107 mg, three-step total yield: 46%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07923573B2 |
| Source dataset | uspto-grants-2011_04 |
| ORD ID | ord-8ebe7aa1344f45c193cfa23ce3b7d8b1 |
| Source note | uspto-grants-2011_04 |