反应详情

According to a method similar to Example (40-2), Example (8-3) and Example (17-4), from tert-butyl 2-(bromomethyl)-3,6-bis(methoxymethoxy)-5-(trifluoromethyl)benzoate (154 mg, 0.34 mmol) obtained in Example (87-1) and methyl (4′-hydroxy-1,1′-biphenyl-4-yl)acetate (80 mg, 0.33 mmol) obtained in Example (6-2), the title compound was obtained (25 mg, three-step total yield: 17%).