HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl 6-(bromomethyl)-2-[(tert-butoxycarbonyl)oxy]-3-(trifluoromethyl)benzoate → HCID 11613340, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl 6-(bromomethyl)-2-[(tert-butoxycarbonyl)oxy]-3-(trifluoromethyl)benzoate | HCID 67119234 | — |
| Reactant | HCID 86241486 | HCID 86241486 | — |
| Product | HCID 11613340 | HCID 11613340 | 13% |
Reaction Steps
According to a method similar to Example (2-3), Example (33-5) and Example (17-4), from methyl [5-(4-hydroxyphenyl)-4-methyl-2-thienyl]acetate (133 mg, 0.51 mmol) obtained in Example (96-4) and tert-butyl 6-(bromomethyl)-2-[(tert-butoxycarbonyl)oxy]-3-(trifluoromethyl)benzoate (254 mg, 0.56 mmol) obtained in Example (28-5), the title compound was obtained as a pale yellow crystal (35 mg, three-step total yield: 13%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07923573B2 |
| Source dataset | uspto-grants-2011_04 |
| ORD ID | ord-f4a217e6e24a4877a4dcc8ac6ba40bad |
| Source note | uspto-grants-2011_04 |