Water → HCID 12007427, compound

Participants

Reaction Steps

2-Amino-4-(2-furyl)thiazole (330 mg, 1.99 mmol) obtained in Step 1 was suspended in chloroform (4 mL). To the suspension was added N-bromosuccinimide (360 mg, 2.02 mmol), and the mixture was stirred at room temperature for 1 hour. Water was added to the reaction mixture, and the mixture was extracted with ethyl acetate. The organic layer was washed with brine and dried over anhydrous magnesium sulfate. The solvent was then evaporated under reduced pressure to give a title compound (438 mg, 90%).

Provenance & Evidence