HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-tert-Butyl 4-ethyl 5-oxoazepane-1,4-dicarboxylate → 1-Tert-butyl 4-ethyl 6-methyl-5-oxoazepane-1,4-dicarboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-tert-Butyl 4-ethyl 5-oxoazepane-1,4-dicarboxylate | HCID 4436570 | — |
| Reactant | tert-Butyl 3-methyl-4-oxopiperidine-1-carboxylate | HCID 22644642 | — |
| Product | 1-Tert-butyl 4-ethyl 6-methyl-5-oxoazepane-1,4-dicarboxylate | HCID 59312224 | 100% |
Reaction Steps
The title compound was prepared by a similar method to that of 1-tert-butyl 4-ethyl 5-oxoazepane-1,4-dicarboxylate (see WO2006029154, example 1a, p 34) from Tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate, yielding 100% of title compound which was taken on for pyrimidone formation without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07928099B2 |
| Source dataset | uspto-grants-2011_04 |
| ORD ID | ord-9df31737def54ed988f99634e85b2c4f |
| Source note | uspto-grants-2011_04 |