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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2077166Generated: October 31, 2026

Glycine → {[1-Cyano-4-hydroxy-8-(2-methoxy-phenoxy)-isoquinoline-3-carbonyl]-amino}-acetic acid

https://huagongshe.com/reaction/2077166

Reaction equation

Participants

RoleNameHCIDCharge
ReactantGlycineHCID 750—
Reactant1-Cyano-4-hydroxy-8-(2-methoxy-phenoxy)-isoquinoline-3-carboxylic acid methyl esterHCID 67110266—
Product{[1-Cyano-4-hydroxy-8-(2-methoxy-phenoxy)-isoquinoline-3-carbonyl]-amino}-acetic acidHCID 24780279—

Reaction Steps

The title compound was synthesized from 1-cyano-4-hydroxy-8-(2-methoxy-phenoxy)-isoquinoline-3-carboxylic acid methyl ester and glycine in analogy to example 1b; MS-(−)-ion: M−1=392.5.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07928120B2
Source datasetuspto-grants-2011_04
ORD IDord-200f12df63514967acf70bc0f3348652
Source noteuspto-grants-2011_04