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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2077185Generated: November 3, 2026

Glycine → {[6-(4-Chloro-2,6-dimethyl-phenoxy)-1-cyano-4-hydroxy-isoquinoline-3-carbonyl]-amino}-acetic acid

https://huagongshe.com/reaction/2077185

Reaction equation

Participants

RoleNameHCIDCharge
ReactantGlycineHCID 750—
ReactantHCID 67110530HCID 67110530—
Product{[6-(4-Chloro-2,6-dimethyl-phenoxy)-1-cyano-4-hydroxy-isoquinoline-3-carbonyl]-amino}-acetic acidHCID 24780415—

Reaction Steps

The title compound was synthesized from 6-(4-Chloro-2,6-dimethyl-phenoxy)-1-cyano-4-hydroxy-isoquinoline-3-carboxylic acid butyl ester and glycine in analogy to example 1b; MS-(−)-ion: M−1=424.3.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07928120B2
Source datasetuspto-grants-2011_04
ORD IDord-61fa399f11b2448da0093faee3a33128
Source noteuspto-grants-2011_04