HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Chloro-1-benzofuran → (RS)-2-[1-(5-Chloro-benzofuran-2-yl)-methanoyl]-4-methyl-piperazine-1-carboxylic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Chloro-1-benzofuran | HCID 90013 | — |
| Reactant | (RS)-2-(methoxy-methyl-carbamoyl)4-methyl-piperazine-1-carboxylic acid dimethyl-ethyl ester | HCID 86625772 | — |
| Product | (RS)-2-[1-(5-Chloro-benzofuran-2-yl)-methanoyl]-4-methyl-piperazine-1-carboxylic acid tert-butyl ester | HCID 66967838 | — |
Reaction Steps
The title compound (0.98 g) was prepared from (RS)-2-(methoxy-methyl-carbamoyl)-4-methyl-piperazine-1-carboxylic acid dimethyl-ethyl ester, D54 (1.60 g) and 5-chloro-benzofuran (0.86 g, FP1.537.206) using the method of Description 2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07928124B2 |
| Source dataset | uspto-grants-2011_04 |
| ORD ID | ord-578821f164ff4204ba422b146f9cb269 |
| Source note | uspto-grants-2011_04 |