Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methylamine → 5-Bromo-N-methyl-3-nitropyridin-2-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methylamine | HCID 6329 | — |
| 반응물 | Tetrahydrofuran | HCID 8028 | — |
| 반응물 | 5-Bromo-2-chloro-3-nitropyridine | HCID 7019412 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 5-Bromo-N-methyl-3-nitropyridin-2-amine | HCID 10868149 | — |
반응 단계
5-bromo-2-chloro-3-nitropyridine (456 mg, 1920 μmol) was dissolved in MeOH (6.0 ml) and methylamine, 2.0 M solution in tetrahydrofuran (2.5 ml, 5.0 mmol) was added. The reaction was stirred at room temperature for 6 hours, allowed to stand at room temperature overnight, and then concentrated. material was taken directly to the next step.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07928140B2 |
| 출처 데이터셋 | uspto-grants-2011_04 |
| ORD ID | ord-477fb39ca8fe4324914ee8e5e98c1828 |
| 출처 메모 | uspto-grants-2011_04 |