Butyryl chloride → 2-[4-(5,7-Dimethyl-2-propyl-3H-imidazo[4,5-b]pyridin-3-yl)phenyl]ethyl butyrate
Reaction equation
[NH2:1][C:2]1[C:3]([NH:10][C:11]2[CH:16]=[CH:15][C:14]([CH2:17][CH2:18][OH:19])=[CH:13][CH:12]=2)=[N:4][C:5]([CH3:9])=[CH:6][C:7]=1[CH3:8].[C:20](Cl)(=[O:24])[CH2:21][CH2:22][CH3:23]>>[C:20]([O:19][CH2:18][CH2:17][C:14]1[CH:15]=[CH:16][C:11]([N:10]2[C:3]3=[N:4][C:5]([CH3:9])=[CH:6][C:7]([CH3:8])=[C:2]3[N:1]=[C:3]2[CH2:2][CH2:7][CH3:6])=[CH:12][CH:13]=1)(=[O:24])[CH2:21][CH2:22][CH3:23]Participants
3
Procedure
The title compound was prepared according to the procedure described in step 5 of Example 1 from 2-{4-[(3-amino-4,6-dimethyl-2-pyridinyl)amino]phenyl}ethanol (step 4 of Example 1) and butyryl chloride.
Sources & evidence
- ORD record
- ord-d3baa81f0be14467badb3dc8f2f1c79e
- Source dataset
- uspto-grants-2011_04
- Patent number
- US07928119B2
Reaction notes
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