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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2077751Generated: October 30, 2026

Pyridine sulfonamide → 2-{4-[6-chloro-2-ethyl-5-(trifluoromethyl)-1H-benzimidazol-1-yl]phenyl}ethyl 2-pyridinylsulfonylcarbamate

https://huagongshe.com/reaction/2077751

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyridine sulfonamideHCID 12000791—
Reactant2-{4-[6-chloro-2-ethyl-5-(trifluoromethyl)-1H-benzimidazol-1-yl]phenyl}ethyl phenyl carbonateHCID 21876409—
Product2-{4-[6-chloro-2-ethyl-5-(trifluoromethyl)-1H-benzimidazol-1-yl]phenyl}ethyl 2-pyridinylsulfonylcarbamateHCID 21876180—

Reaction Steps

The title compound was prepared according to the procedure described in step 2 of Example 243 from 2-pyridinesulfonamide (Naito, T.; et al., Chem. Pharm. Bull., 1955, 3, 38) and 2-[4-(2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl)phenyl]ethylcarbamate (step 1 of Example 243).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07928119B2
Source datasetuspto-grants-2011_04
ORD IDord-9d438b0926f94f67b0e66cfbeebd64a4
Source noteuspto-grants-2011_04