HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl ethyl 2-(6-nitro-3-pyridinyl)malonate → Ethyl 2-(6-nitropyridin-3-yl)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl ethyl 2-(6-nitro-3-pyridinyl)malonate | HCID 21875897 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Ethyl 2-(6-nitropyridin-3-yl)acetate | HCID 21300451 | — |
Reaction Steps
To a solution of benzyl ethyl 2-(6-nitro-3-pyridinyl)malonate (5.26 g, 15.3 mmol,) in ethanol was added palladium on carbon (530 mg) and stirred for 6 h under hydrogen atmosphere at room temperature. The catalyst was filtered off through a pad of celite and the filtrate was concentrated to give a title compound as yellow brown oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07928119B2 |
| Source dataset | uspto-grants-2011_04 |
| ORD ID | ord-c2ea79f70d6545c3ad1b3760b70240ce |
| Source note | uspto-grants-2011_04 |