HCID 67099598, compound → HCID 57983572, compound

Participants

Reaction Steps

A mixture of 1,1-dimethylethyl N-((6′-chloro-4′-hydroxy-2′-oxo-2′H-spiro[cyclopentane-1,1′-naphthalen]-3′-yl)carbonyl)glycinate (0.2 g, 0.5 mmol) in 2 mL TFA was stirred at room temperature for 30 minutes, M+1=350. The mixture was concentrated and triturated in ether/hexane (10:1). The solid was filtered, washed with 10 mL ether/hexane (10:1), and dried under high vacuum to give 135 mg of the salt as an off-white solid. MS (m/z)=350 (M+H)+. Calculated for C17H16ClNO5 349.07.

Provenance & Evidence