Trifluoroacetic acid → HCID 57983520, compound

Participants

Reaction Steps

The mixture of 1,1-dimethylethyl N-((7-chloro-4-hydroxy-2-oxo-2′,3′,5′,6′-tetrahydro-spiro[naphthalene-1,4′-pyran]-3-yl)carbonyl)glycinate (2.23 g, 5 mmol) in TFA (8 mL, 108 mmol) was stirred at room temperature for 20 minutes. The majority of the TFA was removed in vacuo and then water was added. The resulting precipitate was filtered and washed with water to give the desired product as a white solid (1.13 g). MS (m/e)=366.1 (M+H)+. Calculated for C17H16ClNO6 365.07.

Provenance & Evidence