HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → Methyl 2-(4-chloro-2-fluorophenyl)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Sulfuryl chloride | HCID 24648 | — |
| Reactant | (4-Chloro-2-fluorophenyl)acetic acid | HCID 2757563 | — |
| Product | Methyl 2-(4-chloro-2-fluorophenyl)acetate | HCID 57443493 | — |
Reaction Steps
2-(4-Chloro-2-fluorophenyl)acetic acid (25.0 g, 133 mmol) was dissolved in MeOH (133 mL). Sulfuryl dichloride (9.67 mL, 133 mmol) was then added, and the reaction was stirred at ambient temperature for 3 hours. The reaction mixture was concentrated in vacuo to give the title compound which was used without further purification. MS (m/z)=203 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07928139B2 |
| Source dataset | uspto-grants-2011_04 |
| ORD ID | ord-c9d1f31a2d8645fdbcbcabfe89a157d7 |
| Source note | uspto-grants-2011_04 |