HCID 67099890, compound → HCID 57983416, compound

Participants

Reaction Steps

1,1-Dimethylethyl N-((6,7-dichloro-4-hydroxy-2-oxo-2′,3′,5′,6′-tetrahydro-spiro[naphthalene-1,4′-pyran]-3-yl)carbonyl)glycinate (350 mg, 767 μmol) was dissolved in TFA (3 mL). The resulting mixture was stirred for 1 hour and then concentrated, precipitated with hexanes, sonicated, filtered, washed with hexanes, and dried in a vacuum oven to give the title compound (268 mg, 87.3% yield) as a white solid. MS (m/z)=400 (M+H)+. Calculated for C17H15Cl2NO6 399.03.

Provenance & Evidence