HCID 178451285, compound → HCID 178525894, compound

Participants

Reaction Steps

A mixture of t-butyl-N-((5-chloro-2-hydroxy-4-oxo-2′,3′,5′,6′-tetrahydro-4H-spiro[naphthalene-1,4′-pyran]-3-yl)carbonyl)glycinate (51 mg, 121 μmol) in 1 mL TFA was stirred at room temperature for 30 minutes and diluted with 20 mL water. The solid was collected by filtration and washed with 20 mL water. The solid was then dried under high vacuum to give, 39 mg pale yellow solid. MS m/e: (M+H)+ 366.

Provenance & Evidence