HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phthalic Anhydride → (2-Benzyl-3-oxo-2,3-dihydro-1H-isoindol-1-ylsulfanyl)-acetic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phthalic Anhydride | HCID 6811 | — |
| Reactant | Benzylamine | HCID 7504 | — |
| Reactant | (3-Oxo-2-thiophen-2-ylmethyl-2,3-dihydro-1H-isoindol-1-ylsulfanyl)-acetic acid methyl ester | HCID 57679339 | — |
| Product | (2-Benzyl-3-oxo-2,3-dihydro-1H-isoindol-1-ylsulfanyl)-acetic acid ethyl ester | HCID 67096661 | — |
Reaction Steps
Compound 17 was prepared using the synthetic sequence in a manner analogous to the method described for the conversion of commercially available phthalic anhydride to compound 13 using benzylamine instead of thiophene-2-methylamine in the first step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07928246B2 |
| Source dataset | uspto-grants-2011_04 |
| ORD ID | ord-f64b0d2b969c42778afe8d021c4e6a43 |
| Source note | uspto-grants-2011_04 |