HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Aminophenol → 4-(2-(N-isopropylcarbamoyl)-4-pyridyloxy)aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Aminophenol | HCID 403 | — |
| Reactant | Isopropylamine | HCID 6363 | — |
| Reactant | 4-chloropyridine-2-carbonyl Chloride | HCID 11095146 | — |
| Reactant | 4-Chloro-N-isopropyl-pyridine-2-carboxamide | HCID 22832083 | — |
| Product | 4-(2-(N-isopropylcarbamoyl)-4-pyridyloxy)aniline | HCID 23614560 | — |
Reaction Steps
Entry 106: 4-Chloropyridine-2-carbonyl chloride was reacted with isopropylamine according to Method A2, Step 3b. The resulting 4-chloro-N-isopropyl-2-pyridinecarboxamide was reacted with 4-aminophenol according to Method A2, Step 4 to give 4-(2-(N-isopropylcarbamoyl)-4-pyridyloxy)aniline. 3-Amino-2-methoxyquinoline was reacted with 4-(2-(N-isopropylcarbamoyl)-4-pyridyloxy)aniline according to Method C2c to afford the urea.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07928239B2 |
| Source dataset | uspto-grants-2011_04 |
| ORD ID | ord-62cd823eb0e6446696254f7ab06eec56 |
| Source note | uspto-grants-2011_04 |