HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Methylthiophene-2-carboxylic acid → 1-(5-Phenyl-thieno[3,2-c]pyrazol-1-yl)-ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Methylthiophene-2-carboxylic acid | HCID 74713 | — |
| Reactant | Methyl 1-acetyl-1H-thieno[3,2-c]pyrazole-5-carboxylate | HCID 57637373 | — |
| Product | 1-(5-Phenyl-thieno[3,2-c]pyrazol-1-yl)-ethanone | HCID 57637378 | — |
Reaction Steps
1-(5-phenyl-thieno[3,2-c]pyrazol-1-yl)-ethanone [Intermediate (44), LC/MS: 243.1 (M+H), RT=3.45 minutes; 1H NMR (300 Mhz, CDCl3): δ 7.84 (s, 1H), 7.78 (s, 1H), 7.64 (m, 2H), 7.43-7.31 (m, 3H), 2.75 (s, 3H)] is prepared using procedures similar to those described hereinabove for Intermediate (25) substituting 2-phenyl-5-methyl-thiophene for 5-methylthiophene-2-carboxylic acid in step 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07928231B2 |
| Source dataset | uspto-grants-2011_04 |
| ORD ID | ord-0d8f2615a58a427ba20b8b65288f8103 |
| Source note | uspto-grants-2011_04 |