HuagongsheHuagongshe Chemistry Print Report · For research reference only
methyl 4-(8-bromo-N-methyl-4,5-dihydrobenzo[b]thieno[2,3-d]oxepine-2-carboxamido)-3-chlorobenzoate → methyl 3-chloro-4-(8-cyano-N-methyl-4,5-dihydrobenzo[b]thieno[2,3-d]oxepine-2-carboxamido)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | methyl 4-(8-bromo-N-methyl-4,5-dihydrobenzo[b]thieno[2,3-d]oxepine-2-carboxamido)-3-chlorobenzoate | HCID 56834273 | — |
| Reactant | HCID 178418546 | HCID 178418546 | — |
| Product | methyl 3-chloro-4-(8-cyano-N-methyl-4,5-dihydrobenzo[b]thieno[2,3-d]oxepine-2-carboxamido)benzoate | HCID 57900361 | — |
Reaction Steps
Following Example 53, methyl 4-(8-bromo-N-methyl-4,5-dihydrobenzo[b]thieno[2,3-d]oxepine-2-carboxamido)-3-chlorobenzoate and CuCN gave methyl 3-chloro-4-(8-cyano-N-methyl-4,5-dihydrobenzo[b]thieno[2,3-d]oxepine-2-carboxamido)benzoate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07928248B2 |
| Source dataset | uspto-grants-2011_04 |
| ORD ID | ord-fab061e4b33644c484defe4ff731d408 |
| Source note | uspto-grants-2011_04 |