HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thiosemicarbazide → HCID 57900121, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thiosemicarbazide | HCID 2723789 | — |
| Reactant | 4,7-dibromo-3,4-dihydrobenzo[b]oxepin-5(2H)-one | HCID 57900458 | — |
| Product | HCID 57900121 | HCID 57900121 | — |
Reaction Steps
Following the procedure for 449, Step 2, 4,7-dibromo-3,4-dihydro-2H-benzo[b]oxepin-5-one was reacted with thiosemicarbazide to afford the title compound as a beige solid. LCMS (Method E): RT=3.85 min, [M+H]+=312 and 314. 1H NMR (DMSO-d6): 10.13 (2H, bs), 9.80 (1H, bs), 8.49 (1H, d, J=2.6 Hz), 7.37 (1H, dd, J=8.6, 2.6 Hz), 6.97 (1H, d, J=8.6 Hz), 4.29 (2H, t, J=5.0 Hz), 3.21 (2H, t, J=5.0 Hz).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07928248B2 |
| Source dataset | uspto-grants-2011_04 |
| ORD ID | ord-13fa39e2057c48d4a6816281618e4010 |
| Source note | uspto-grants-2011_04 |