Ethyl 3,3-dimethylspiro[bicyclo[2.2.1]heptane-2,1'-cyclopropane]-2'-carboxylate → 3,3-Dimethylspiro[bicyclo[2.2.1]heptane-2,1'-cyclopropane]-2'-carboxylic acid

HRID 2079474Notes

Reaction equation

HRID 2079474 reaction equation
[CH3:1][C:2]1([CH3:16])[C:8]2([CH2:10][CH:9]2[C:11]([O:13]CC)=[O:12])[CH:6]2[CH2:7][CH:3]1[CH2:4][CH2:5]2.C1(C(OCC)=O)C2(CCCCC2)C1>>[CH3:1][C:2]1([CH3:16])[C:8]2([CH2:10][CH:9]2[C:11]([OH:13])=[O:12])[CH:6]2[CH2:7][CH:3]1[CH2:4][CH2:5]2

Participants

3

Reactant 2

HCID 255826Ethyl 3,3-dimethylspiro[bicyclo[2.2.1]heptane-2,1'-cyclopropane]-2'-carboxylateHCID 11206164Ethyl Spiro[2.5]octane-1-carboxylate

Product 1

HCID 104201543,3-Dimethylspiro[bicyclo[2.2.1]heptane-2,1'-cyclopropane]-2'-carboxylic acid

Procedure

The title compound was prepared as described in Example 1B substituting the product from Example 30A for the product from Example 1A. MS m/z 194 (M)+.

Sources & evidence

ORD record
ord-c82e166ad4fc44f083f7f6010ea07b6c
Source dataset
uspto-grants-2011_04
Patent number
US07932245B2

Reaction notes

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