Ethyl Spiro[2.5]octane-1-carboxylate → 4-Methylspiro[bicyclo[3.2.0]heptane-6,1'-cyclopropane]-2'-carboxylic acid

HRID 2079475Notes

Reaction equation

HRID 2079475 reaction equation
[CH3:1][CH:2]1[CH:15]2[CH:5]([CH2:6][C:7]32[CH2:9][CH:8]3[C:10]([O:12]CC)=[O:11])[CH2:4][CH2:3]1.C1(C(OCC)=O)C2(CCCCC2)C1>>[CH3:1][CH:2]1[CH:15]2[CH:5]([CH2:6][C:7]32[CH2:9][CH:8]3[C:10]([OH:12])=[O:11])[CH2:4][CH2:3]1

Participants

3

Reactant 2

HCID 11206164Ethyl Spiro[2.5]octane-1-carboxylateHCID 67103211Ethyl 4-methylspiro[bicyclo[3.2.0]heptane-6,1'-cyclopropane]-2'-carboxylate

Product 1

HCID 113213084-Methylspiro[bicyclo[3.2.0]heptane-6,1'-cyclopropane]-2'-carboxylic acid

Procedure

The title compound was prepared as described in Example 1B substituting the product from Example 33B for the product from Example 1A. MS (ESI) m/z 179 (M−H)−.

Sources & evidence

ORD record
ord-81263f1dfe2c4ae6ad5a92c0b90d80ac
Source dataset
uspto-grants-2011_04
Patent number
US07932245B2

Reaction notes

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