Ethyl Spiro[2.5]octane-1-carboxylate → octahydro-1'H-spiro[cyclopropane-1,2'-naphthalene]-2-carboxylic acid

HRID 2079480Notes

Reaction equation

HRID 2079480 reaction equation
[CH2:1]1[CH:10]2[CH:5]([CH2:6][CH2:7][CH2:8][CH2:9]2)[CH2:4][CH2:3][C:2]21[CH2:12][CH:11]2[C:13]([O:15]CC)=[O:14].C1(C(OCC)=O)C2(CCCCC2)C1>>[CH2:1]1[CH:10]2[CH:5]([CH2:6][CH2:7][CH2:8][CH2:9]2)[CH2:4][CH2:3][C:2]21[CH2:12][CH:11]2[C:13]([OH:15])=[O:14]

Participants

3

Reactant 2

HCID 11206164Ethyl Spiro[2.5]octane-1-carboxylateHCID 67102758ethyl octahydro-1'H-spiro[cyclopropane-1,2'-naphthalene]-2-carboxylate

Product 1

HCID 10058899octahydro-1'H-spiro[cyclopropane-1,2'-naphthalene]-2-carboxylic acid

Procedure

The title compound was prepared as described in Example 1B substituting the product from Example 45B for the product from Example 1A. MS m/z 208 (M)+.

Sources & evidence

ORD record
ord-a43083e93cb5467291cd88cd3cfdb6be
Source dataset
uspto-grants-2011_04
Patent number
US07932245B2

Reaction notes

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