4-t-Butylbenzenesulfonyl chloride → HCID 58398280, compound

HRID 2079493Notes

Reaction equation

HRID 2079493 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([NH2:8])=[C:4]([C:9]([F:17])([F:16])[C:10]2[CH:15]=[CH:14][N:13]=[CH:12][CH:11]=2)[CH:3]=1.[C:18]([C:22]1[CH:27]=[CH:26][C:25]([S:28](Cl)(=[O:30])=[O:29])=[CH:24][CH:23]=1)([CH3:21])([CH3:20])[CH3:19]>>[C:18]([C:22]1[CH:27]=[CH:26][C:25]([S:28]([NH:8][C:5]2[CH:6]=[CH:7][C:2]([Cl:1])=[CH:3][C:4]=2[C:9]([F:17])([F:16])[C:10]2[CH:15]=[CH:14][N:13]=[CH:12][CH:11]=2)(=[O:30])=[O:29])=[CH:24][CH:23]=1)([CH3:21])([CH3:19])[CH3:20]

Participants

3

Reactant 2

HCID 1398824-t-Butylbenzenesulfonyl chlorideHCID 58398272HCID 58398272, compound

Product 1

HCID 58398280HCID 58398280, compound

Procedure

The title compound was prepared according to the general procedure for the preparation of N-Aryl-benzenesulfonamides using 4-chloro-2-(difluoro-pyridin-4-yl-methyl)-phenylamine and 4-tert-butyl-benzenesulfonyl chloride. MS: (M+H)=451.

Sources & evidence

ORD record
ord-9f3baa3b7d814e8c8ddfe3d9c38be220
Source dataset
uspto-grants-2011_04
Patent number
US07932252B2

Reaction notes

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