HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2079496Generated: October 25, 2026
Potassium Carbonate → 4-tert-Butyl-N-[4-chloro-2-(methoxy-pyridin-4-yl-methyl)-Phenyl]-benzenesulfonamide
https://huagongshe.com/reaction/2079496
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-tert-Butyl-N-[4-chloro-2-(chloro-pyridin-4-yl-methyl)-phenyl]-benzenesulfonamide | HCID 59485502 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-tert-Butyl-N-[4-chloro-2-(methoxy-pyridin-4-yl-methyl)-Phenyl]-benzenesulfonamide | HCID 59756865 | — |
Reaction Steps
A suspension of 4-tert-butyl-N-[4-chloro-2-(chloro-pyridin-4-yl-methyl)-phenyl]-benzenesulfonamide (113 mg, 0.25 mmol) and potassium carbonate (69 mg, 0.5 mmol) in anhydrous methanol was heated at 60° C. overnight, the solid residue was then removed by filtration and product was purified by preparative HPLC. MS: (M+H)=445.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07932252B2 |
|---|
| Source dataset | uspto-grants-2011_04 |
|---|
| ORD ID | ord-8243154651194dda942bd5f33ca62a72 |
|---|
| Source note | uspto-grants-2011_04 |
|---|
