4-(1,3-Oxazol-5-yl)benzenesulphonyl chloride → HCID 58398309, compound

HRID 2079499Notes

Reaction equation

HRID 2079499 reaction equation
[O:1]1[C:5]([C:6]2[CH:11]=[CH:10][C:9]([S:12](Cl)(=[O:14])=[O:13])=[CH:8][CH:7]=2)=[CH:4][N:3]=[CH:2]1.[Cl:16][C:17]1[CH:22]=[CH:21][C:20]([NH2:23])=[C:19]([C:24]2[C:33]3[C:28](=[CH:29][CH:30]=[CH:31][CH:32]=3)[CH:27]=[CH:26][N:25]=2)[CH:18]=1>>[Cl:16][C:17]1[CH:22]=[CH:21][C:20]([NH:23][S:12]([C:9]2[CH:10]=[CH:11][C:6]([C:5]3[O:1][CH:2]=[N:3][CH:4]=3)=[CH:7][CH:8]=2)(=[O:14])=[O:13])=[C:19]([C:24]2[C:33]3[C:28](=[CH:29][CH:30]=[CH:31][CH:32]=3)[CH:27]=[CH:26][N:25]=2)[CH:18]=1

Participants

3

Reactant 2

HCID 27764154-(1,3-Oxazol-5-yl)benzenesulphonyl chlorideHCID 13805401HCID 13805401, compound

Product 1

HCID 58398309HCID 58398309, compound

Procedure

The title compound was prepared according to the general procedure using 4-oxazol-5-yl-benzenesulfonyl chloride and 4-chloro-2-isoquinolin-1-yl-phenylamine and purified by preparative HPLC. MS: (M+H)/z=462.

Workup

  1. custompurified by preparative HPLC

Sources & evidence

ORD record
ord-b42fcfed83034c3e9b2f679363f55ec5
Source dataset
uspto-grants-2011_04
Patent number
US07932252B2

Reaction notes

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