(2-Amino-5-bromo-3-methoxyphenyl)methanol → 2-Amino-5-bromo-3-methoxybenzaldehyde

Participants

Reaction Steps

To a 0.15 M chloroform solution of (2-amino-5-bromo-3-methoxyphenyl)methanol (10.16 g, 43.96 mmol) was added manganese dioxide (19.9 g, 280.5 mmol). The mixture was stirred under argon at room temperature for 16 hours. The resulting mixture was filtered through celite and washed with dichloromethane. The filtrate was concentrated to dryness and used in next step. ES/MS m/z 228/230 (MH+).

Provenance & Evidence