HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2-Amino-3-bromo-5-fluorophenyl)methanol → 2-Amino-3-bromo-5-fluorobenzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2-Amino-3-bromo-5-fluorophenyl)methanol | HCID 53871442 | — |
| Catalyst | HCID 178418406 | HCID 178418406 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2-Amino-3-bromo-5-fluorobenzaldehyde | HCID 59325487 | — |
Reaction Steps
Manganese (IV) oxide (5 eq) was added to a 0.2M solution of (2-amino-3-bromo-5-fluorophenyl)methanol in dichloromethane. The suspension was stirred at ambient temperature under Argon for 12 h. The reaction mixture was filtered through celite and filter cake was washed with dichloromethane. The combined filtrate was concentrated to give brown color solid. ES/MS m/z 218/220 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07932262B2 |
| Source dataset | uspto-grants-2011_04 |
| ORD ID | ord-19cd4c8288114f409ab813dbb539bfaf |
| Source note | uspto-grants-2011_04 |