HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,1-Dimethylethyl 6-(2-quinolinylamino)-3-azabicyclo[3.1.0]hexane-3-carboxylate → HCID 43599085, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,1-Dimethylethyl 6-(2-quinolinylamino)-3-azabicyclo[3.1.0]hexane-3-carboxylate | HCID 59367599 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 43599085 | HCID 43599085 | — |
Reaction Steps
tert-Butyl 6-(quinolin-2-ylamino)-3-azabicyclo[3.1.0]hexane-3-carboxylate (320 mg, 0.98 mmol) was stirred in 4M HCl in dioxane (2 ml) at r.t. under N2 for 15 min. The solvent was then removed in vacuo and the residue dried under high-vacuum and used in the next step without further purification. LCMS purity 91%, m/z 226 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07932246B2 |
| Source dataset | uspto-grants-2011_04 |
| ORD ID | ord-2dcd32c3ced94f348897428525960df5 |
| Source note | uspto-grants-2011_04 |