4-(1-Pyrrolidinyl)piperidine → HCID 135987498, compound

HRID 2079866Notes

Reaction equation

HRID 2079866 reaction equation
C([O:8][C:9]1[CH:14]=[C:13]([O:15]CC2C=CC=CC=2)[C:12]([C:23]2[N:27]([CH2:28][CH2:29][CH2:30][CH3:31])[N:26]=[N:25][N:24]=2)=[CH:11][C:10]=1[C:32]1[CH:37]=[CH:36][CH:35]=[C:34]([C:38](O)=[O:39])[CH:33]=1)C1C=CC=CC=1.[N:41]1([CH:46]2[CH2:51][CH2:50][NH:49][CH2:48][CH2:47]2)[CH2:45][CH2:44][CH2:43][CH2:42]1>>[CH2:28]([N:27]1[C:23]([C:12]2[C:13]([OH:15])=[CH:14][C:9]([OH:8])=[C:10]([C:32]3[CH:37]=[CH:36][CH:35]=[C:34]([C:38]([N:49]4[CH2:50][CH2:51][CH:46]([N:41]5[CH2:45][CH2:44][CH2:43][CH2:42]5)[CH2:47][CH2:48]4)=[O:39])[CH:33]=3)[CH:11]=2)=[N:24][N:25]=[N:26]1)[CH2:29][CH2:30][CH3:31]

Participants

3

Reactant 2

HCID 787034-(1-Pyrrolidinyl)piperidineHCID 57695592HCID 57695592, compound

Product 1

HCID 135987498HCID 135987498, compound

Procedure

This product was synthesized using 2′,4′-bis-benzyloxy-5′-(1-butyl-1H-tetrazol-5-yl)-biphenyl-3-carboxylic acid and 4-(1-pyrrolidinyl)piperidine as described in general procedure D. LCMS: 491 [M+H].

Workup

  1. customThis product was synthesized

Sources & evidence

ORD record
ord-546899bba5ca4c26aec265cd3373f0e2
Source dataset
uspto-grants-2011_04
Patent number
US07932279B2

Reaction notes

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