1-(Ethanesulfonyl)piperazine → HCID 136382862, compound
Reaction equation
C([O:8][C:9]1[CH:14]=[C:13]([O:15]CC2C=CC=CC=2)[C:12]([C:23]2[N:27]([CH2:28][CH2:29][CH2:30][O:31][CH3:32])[N:26]=[N:25][N:24]=2)=[CH:11][C:10]=1[C:33]1[CH:38]=[CH:37][CH:36]=[C:35]([C:39](O)=[O:40])[CH:34]=1)C1C=CC=CC=1.[CH2:42]([S:44]([N:47]1[CH2:52][CH2:51][NH:50][CH2:49][CH2:48]1)(=[O:46])=[O:45])[CH3:43]>>[OH:8][C:9]1[CH:14]=[C:13]([OH:15])[C:12]([C:23]2[N:27]([CH2:28][CH2:29][CH2:30][O:31][CH3:32])[N:26]=[N:25][N:24]=2)=[CH:11][C:10]=1[C:33]1[CH:38]=[CH:37][CH:36]=[C:35]([C:39]([N:50]2[CH2:49][CH2:48][N:47]([S:44]([CH2:42][CH3:43])(=[O:45])=[O:46])[CH2:52][CH2:51]2)=[O:40])[CH:34]=1Participants
3
Procedure
This product was synthesized using 2′,4′-bis-benzyloxy-5′-[1-(3-methoxy-propyl)-1H-tetrazol-5-yl]-biphenyl-3-carboxylic acid and 1-ethylsulfonyl piperazine as described in general procedure D. LCMS: 531 [M+H].
Workup
- customThis product was synthesized
Sources & evidence
- ORD record
- ord-e0bd1fa719274b3c936e7c07709ad4c9
- Source dataset
- uspto-grants-2011_04
- Patent number
- US07932279B2
Reaction notes
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