1-((1-Methyl-4-piperidinyl)methyl)piperazine → HCID 135987555, compound

HRID 2079873Notes

Reaction equation

HRID 2079873 reaction equation
C([O:8][C:9]1[CH:14]=[C:13]([O:15]CC2C=CC=CC=2)[C:12]([C:23]2[N:27]([CH2:28][CH2:29][CH2:30][O:31][CH3:32])[N:26]=[N:25][N:24]=2)=[CH:11][C:10]=1[C:33]1[CH:38]=[CH:37][CH:36]=[C:35]([C:39]([OH:41])=O)[CH:34]=1)C1C=CC=CC=1.[CH3:42][N:43]1[CH2:48][CH2:47][CH:46]([CH2:49][N:50]2[CH2:55][CH2:54][NH:53][CH2:52][CH2:51]2)[CH2:45][CH2:44]1>>[OH:8][C:9]1[CH:14]=[C:13]([OH:15])[C:12]([C:23]2[N:27]([CH2:28][CH2:29][CH2:30][O:31][CH3:32])[N:26]=[N:25][N:24]=2)=[CH:11][C:10]=1[C:33]1[CH:38]=[CH:37][CH:36]=[C:35]([C:39]([N:53]2[CH2:52][CH2:51][N:50]([CH2:49][CH:46]3[CH2:47][CH2:48][N:43]([CH3:42])[CH2:44][CH2:45]3)[CH2:55][CH2:54]2)=[O:41])[CH:34]=1

Participants

3

Procedure

This product was synthesized using 2′,4′-bis-benzyloxy-5′-[1-(3-methoxy-propyl)-1H-tetrazol-5-yl]-biphenyl-3-carboxylic acid and 1-(N-methylpiperidin-4-yl-methyl)piperazine as described in general procedure D. LCMS: 550 [M+H].

Workup

  1. customThis product was synthesized

Sources & evidence

ORD record
ord-68567f9a2fa640bfbe83aac616d05359
Source dataset
uspto-grants-2011_04
Patent number
US07932279B2

Reaction notes

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