1-[2-(Pyrrolidin-1-yl)ethyl]piperazine → HCID 135987568, compound

HRID 2079874Notes

Reaction equation

HRID 2079874 reaction equation
C([O:8][C:9]1[CH:14]=[C:13]([O:15]CC2C=CC=CC=2)[C:12]([C:23]2[N:27]([CH2:28][CH2:29][CH2:30][O:31][CH3:32])[N:26]=[N:25][N:24]=2)=[CH:11][C:10]=1[C:33]1[CH:38]=[CH:37][CH:36]=[C:35]([C:39](O)=[O:40])[CH:34]=1)C1C=CC=CC=1.[N:42]1([CH2:47][CH2:48][N:49]2[CH2:54][CH2:53][NH:52][CH2:51][CH2:50]2)[CH2:46][CH2:45][CH2:44][CH2:43]1>>[OH:8][C:9]1[CH:14]=[C:13]([OH:15])[C:12]([C:23]2[N:27]([CH2:28][CH2:29][CH2:30][O:31][CH3:32])[N:26]=[N:25][N:24]=2)=[CH:11][C:10]=1[C:33]1[CH:38]=[CH:37][CH:36]=[C:35]([C:39]([N:52]2[CH2:51][CH2:50][N:49]([CH2:48][CH2:47][N:42]3[CH2:43][CH2:44][CH2:45][CH2:46]3)[CH2:54][CH2:53]2)=[O:40])[CH:34]=1

Participants

3

Reactant 2

HCID 27372501-[2-(Pyrrolidin-1-yl)ethyl]piperazineHCID 57695565HCID 57695565, compound

Product 1

HCID 135987568HCID 135987568, compound

Procedure

This product was synthesized using template 2′,4′-bis-benzyloxy-5′-(1-butyl-1H-tetrazol-5-yl)-biphenyl-3-carboxylic acid (44) and 1-(2-pyrrolidinoethyl)-piperazine as described in general procedure D. LCMS: 536 [M+H].

Workup

  1. customThis product was synthesized

Sources & evidence

ORD record
ord-3f57df96218c4b8ca2f00dc76acd6924
Source dataset
uspto-grants-2011_04
Patent number
US07932279B2

Reaction notes

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