HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethyl phosphite → Phosphonic acid, [(3-cyanophenyl)methyl]-, diethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethyl phosphite | HCID 31215 | — |
| Reactant | Benzonitrile, 3-(bromomethyl)- | HCID 97249 | — |
| Product | Phosphonic acid, [(3-cyanophenyl)methyl]-, diethyl ester | HCID 21466817 | 79.1% |
Reaction Steps
3-Cyanobenzyl bromide (9.8 g, 50 mmol) and triethylphosphite (9.97 g, 60 mmol) were stirred at 140° C. for 3 hours. The resulting residue was evaporated, the distillate which has 145° C./1 mmHg was collected, and the title compound (10 g, 39.5 mmol, 79.1%) was obtained as a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07932272B2 |
| Source dataset | uspto-grants-2011_04 |
| ORD ID | ord-479d8d2d8a2a4504b2c621d45d245b55 |
| Source note | uspto-grants-2011_04 |