Lithium → Furo[2,3-b]pyridine-5-carboxylic acid

HRID 2080253Notes

Reaction equation

[Li].C([O:4][C:5]([C:7]1[CH:8]=[C:9]2[CH:15]=[CH:14][O:13][C:10]2=[N:11][CH:12]=1)=[O:6])C>>[O:13]1[C:10]2=[N:11][CH:12]=[C:7]([C:5]([OH:6])=[O:4])[CH:8]=[C:9]2[CH:15]=[CH:14]1

Participants

Reactant 2

HCID 3028194Lithium

HCID 10176480HCID 10176480, compound

Product 1

HCID 14372168Furo[2,3-b]pyridine-5-carboxylic acid

Procedure

Furo[2,3-b]pyridine-5-carboxylic acid (31 mg) was obtained as a lithium salt from furo[2,3-b]pyridine-5-carboxylic acid ethyl ester described in Preparation Example P-4 (33 mg, 0.17 mmol) according to an analogous method to Example T-2.

Sources & evidence

ORD record: ord-f204836b6e8d432b9677faf7c57d829d
Source dataset: uspto-grants-2011_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07932272B2

Reaction notes

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