Acetone → Ethyl 4-(2-hydroxypropan-2-yl)-2-propyl-1-((2'-(1-trityl-1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-1H-imidazole-5-carboxylate
Reaction equation
[Br-:62].[C:56](=[O:57])([O-:58])[O-:59].[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[c:7]([C:14]([CH3:15])([CH3:16])[OH:17])[n:8][c:9]([CH2:11][CH2:12][CH3:13])[nH:10]1.[CH2:63]([N+:64]([CH2:65][CH2:66][CH2:67][CH3:68])([CH2:69][CH2:70][CH2:71][CH3:72])[CH2:73][CH2:74][CH2:75][CH3:76])[CH2:77][CH2:78][CH3:79].[CH3:80][C:81](=[O:82])[CH3:83].[CH3:84][C:85]#[N:86].[K+:60].[K+:61].[c:18]1([C:24]([n:25]2[n:26][n:27][n:28][c:29]2-[c:30]2[c:31](-[c:36]3[cH:37][cH:38][c:39]([CH2:42][Br:43])[cH:40][cH:41]3)[cH:32][cH:33][cH:34][cH:35]2)([c:44]2[cH:45][cH:46][cH:47][cH:48][cH:49]2)[c:50]2[cH:51][cH:52][cH:53][cH:54][cH:55]2)[cH:19][cH:20][cH:21][cH:22][cH:23]1>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[c:7]([C:14]([CH3:15])([CH3:16])[OH:17])[n:8][c:9]([CH2:11][CH2:12][CH3:13])[n:10]1[CH2:42][c:39]1[cH:38][cH:37][c:36](-[c:31]2[c:30](-[c:29]3[n:25]([C:24]([c:18]4[cH:19][cH:20][cH:21][cH:22][cH:23]4)([c:44]4[cH:45][cH:46][cH:47][cH:48][cH:49]4)[c:50]4[cH:51][cH:52][cH:53][cH:54][cH:55]4)[n:26][n:27][n:28]3)[cH:35][cH:34][cH:33][cH:32]2)[cH:41][cH:40]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-ab6f197765c140149df8a43d37020e23
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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